CREATE Medicines, Inc.

About CREATE Medicines, Inc.

CREATE Medicines is pioneering multi-immune programming with its versatile in vivo CAR platform. The company focuses on engineering cures from within by programming immune cells such as T cells, NK cells, and myeloid cells directly in the body using proprietary mRNA-LNP CARs and targeted receptor/LNP technologies. Their mission is to unlock scalable, off-the-shelf therapies with speed, lower costs, and broader patient access across cancer, autoimmunity, and fibrosis.

Products & Services

In Vivo CAR Platform:A versatile platform using mRNA-LNP CARs and targeted receptor/LNP technologies to program multiple immune cell types (T, NK, myeloid) within the body, with demonstrated tolerability and first-in-human evidence.

MT-303:A novel GPC3-targeting RNA CAR for advanced hepatocellular carcinoma (HCC), currently in Phase 1 study with patient dosing initiated.

CRT-402

CRT-403

RetroT

MT-302

MT-303

MT-304

CRT-401

Specialties

Multi-immune programming In vivo CAR therapies RNA engineering Selective receptor design Targeted LNP delivery Immunology multi-immune programming in vivo CAR platform mRNA-LNP CARs targeted receptor/LNP technologies T/NK/myeloid cell programming

Funding History

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#	Type	Amount Fields	Date Fields	Investors
1	RT: Series B T: - FT: Series B	A: 122000000 MR: - FA: $122 million FAN: 122000000	D: 2026-05-14 FD: 2026-05-14	4 investors

Series B Latest

2026-05-14

$122.0M

4 investors (Pro only)

Growth Metrics

+45%

Employee Growth

YoY

3.2x

Funding Growth

Last Round

12

Markets

Operating

10K+

Customers

Active

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Team & Leadership

D

Daniel Getts

Chief Executive Officer, Cofounder, Board Director

B

Brett Kaplan

Chief Financial Officer and Chief Business Officer

M

Matthew Maurer

Chief Medical Officer

R

Robert Hofmeister

Chief Scientific Officer

J

Jerome Chal

Chief Technology Officer

C

Curtis Demick

Chief People Officer

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