Spyre Therapeutics

About Spyre Therapeutics

Spyre Therapeutics is dedicated to developing next-generation antibodies for the treatment of inflammatory bowel disease (IBD) and other immune-mediated diseases. Their mission is to transform the lives of patients and caregivers by engineering innovative therapies with prolonged activity and convenient delivery options, aiming for uncompromising efficacy.

Products & Services

SPY001:Targets α4β7, currently in development for gastrointestinal and rheumatic conditions.

SPY003:Targets IL-23, aimed at treating immune-mediated diseases.

SPY120:Combination therapy targeting α4β7 and TL1A.

Specialties

Next-generation antibodies Inflammatory Bowel Disease (IBD) treatment Immune-mediated diseases Half-life extension of therapies Combination therapies

Funding History

Debug: View Raw Funding Data

#	Type	Amount Fields	Date Fields	Investors
1	RT: Public Offering T: - FT: Public Offering	A: 316200000 MR: - FA: 316.2 million FAN: 316200000	D: 2025-10-15 FD: 2025-10-15	5 investors
2	RT: Public Offering T: - FT: Public Offering	A: 275000000 MR: - FA: $275.0 million FAN: 275000000	D: 2025-10-13 FD: 2025-10-13	5 investors
3	RT: Public Offering of Common Stock T: - FT: Public Offering of Common Stock	A: 200000000 MR: - FA: $200.0 million FAN: 200000000	D: 2024-11-18 FD: 2024-11-18	5 investors

Public Offering Latest

2025-10-15

$316.2M

5 investors (Pro only)

Public Offering 2025-10-13

$275.0M

Public Offering of Common Stock 2024-11-18

$200.0M

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Growth Metrics

+45%

Employee Growth

YoY

3.2x

Funding Growth

Last Round

12

Markets

Operating

10K+

Customers

Active

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Team & Leadership

S

Scott Burrows

Chief Financial Officer

LinkedIn (Pro only)

J

Jonathan Campbell

VP, Corporate Controller

LinkedIn (Pro only)

I

Irving Cassidy

VP, Medical Affairs

LinkedIn (Pro only)

B

Brian Connolly

Chief Technical Officer

M

Melissa Cooper

SVP, People

C

Cristina Damatarca

SVP, Drug Safety and Pharmacovigilance

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